Repository of Research and Investigative Information

Repository of Research and Investigative Information

Larestan University of Medical Sciences

Calcium carbonate nanowires: greener biosynthesis and their leishmanicidal activity

(2020) Calcium carbonate nanowires: greener biosynthesis and their leishmanicidal activity. Rsc Advances. pp. 38063-38068.

[img]
Preview
Text
Calcium carbonate nanowires.pdf

Download (733kB) | Preview

Official URL: http://apps.webofknowledge.com/InboundService.do?F...

Abstract

The synthesis of inorganic rod shape nanostructures is important in chromatography, dentistry, and medical applications such as bone implants, and drug and gene delivery systems. Herein, calcium carbonate (CaCO3) nanowires were synthesized using a plant extract and the ensuing nanoparticles were characterized by XRD, FESEM, and HR-TEM. Then, the leishmanicidal effects of biogenic calcium carbonate nanowires were investigated against Leishmania major including the toxicity of varying concentrations of nanoparticles, and the percentage of viable and apoptotic cells based on flow cytometry analysis. Based on the results, the IC50 of these polymorphs were calculated to be 800 mu g mL(-1). An ecofriendly, inexpensive, and novel biogenic method for the production of a new advanced inorganic nanostructure, CaCO3 nanowires, is described without using hazardous chemicals; calcium carbonate nanowires maybe used as a smart drug carrier.

Item Type: Article
Keywords: silver nanoparticles antifungal vaterite fabrication scaffolds cao Chemistry
Divisions: Education Vice-Chancellor Department > Faculty of Nursing and Midwifery > Department of Nursing
Page Range: pp. 38063-38068
Journal or Publication Title: Rsc Advances
Journal Index: ISI
Volume: 10
Number: 62
Identification Number: https://doi.org/10.1039/d0ra04503a
Depositing User: خانم موهبت شیوخی
URI: http://eprints.larums.ac.ir/id/eprint/308

Actions (login required)

View Item View Item